Written by Maria Myers (IBCLC)
Breastfeeding is a unique period requiring a balanced approach to maternal health. As weight-loss medications like Ozempic, Wegovy, and Mounjaro (all semaglutides) become more popular, many breastfeeding mothers are asking: Can these medications be safely used while breastfeeding?
What Are Ozempic, Wegovy, and Mounjaro?
Ozempic, Wegovy, and Mounjaro are all brand names for medications in the semaglutide family, originally designed to manage Type 2 diabetes and, more recently, approved for weight loss. These medications work by increasing insulin secretion, slowing digestion, and ultimately reducing appetite and supporting weight loss. Although results are impressive, these drugs are newer, and their impact on breastfeeding mothers and infants is less understood.
The Function of Semaglutides in the Body
Semaglutides help lower blood glucose levels and manage weight through unique pathways in the body. They stimulate insulin production while also slowing gastric emptying, contributing to a feeling of fullness that can aid weight control. Their potential to pass into breast milk is low due to high molecular weight and protein binding, making it unlikely that infants will absorb the medication through breastfeeding. However, caution is advised since there are limited studies on semaglutide use in breastfeeding mothers.
Limited Research on Semaglutides and Breastfeeding
Current research on semaglutides like Ozempic, Wegovy, and Mounjaro during breastfeeding is sparse. Based on their molecular structure, only minimal amounts would be expected to transfer into breast milk. According to research from the Drugs and Lactation Database and Elactancia, semaglutides are unlikely to pose risks due to their minimal oral bioavailability in infants. Nonetheless, health experts recommend caution, especially in nursing newborns or premature infants who may have higher absorption rates.
Guidelines for Safe Use of Semaglutides While Breastfeeding
Given the limited evidence, breastfeeding mothers considering these medications for weight loss or diabetes management should consult both a healthcare provider and an International Board-Certified Lactation Consultant (IBCLC). The IBCLC can assist with monitoring milk supply and baby’s weight, ensuring that both are on track. This is especially critical when semaglutides are prescribed for weight management, as drastic weight loss may interfere with milk flow, though the body generally prioritises milk quality.
If Using Semaglutides for Diabetes Management
For those needing semaglutides to control Type 2 diabetes, extra monitoring with an IBCLC is advised. They can support you in observing your infant’s response, focusing on weight gain, output, and overall health, while collaborating with your healthcare provider to establish a safe dosage and application schedule.
Using Semaglutides Solely for Weight Loss
If your interest in semaglutides is primarily for weight loss, it’s wise to set gradual weight-loss goals rather than opting for rapid results. Extreme dieting or stress on the body can slow milk flow, affecting breastfeeding. Supporting your body with adequate nutrients or supplements can ensure both you and your baby thrive.
Practical Recommendations for Nursing Mothers on Semaglutides
- Consult Professionals: Seek advice from healthcare providers and IBCLCs about appropriate dosing and application while breastfeeding.
- Monitor Baby’s Health: Keep an eye on changes in your infant’s weight, feeding behaviour, and nappy output. Regular check-ups can help ensure their well-being.
- Timing of Dosages: Timing your doses right after breastfeeding may minimise medication levels in milk at the next feeding.
In conclusion, while semaglutides appear low-risk during breastfeeding due to limited transfer into breast milk, professional guidance is crucial for both diabetes management and safe weight-loss practices. For those seeking weight loss, lifestyle adjustments or alternative therapies may also be worth exploring.
References for Further Reading
- Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-. Semaglutide. [Updated 2024 Oct 15]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK500980/
- Medically reviewed by Amber R. Watson, PharmD — Written by MNT Medical Network on April 4, 2024 Ozempic: Pregnancy and breastfeeding. Available from: https://www.medicalnewstoday.com/articles/drugs-ozempic-reproductive-health
- Elactancia Is it compatible with breastfeeding? https://www.e-lactancia.org/
- Wendy Jones. Semaglutide and Breastfeeding 2024. Available from: https://breastfeeding-and-medication.co.uk/fact-sheet/semaglutide-and-breastfeeding
